Cassoni, Ana C.Freixo, RicardoPintado, Ana I. E.Amorim, ManuelaPereira, Carlos D.Madureira, Ana RaquelPintado, Manuela M. E.2018-12-202018-12-202018Cassoni, A.C.; Freixo, R.; Pintado, A.I.E.; Amorim, M.; Pereira, C.D.; Madureira, A.R.; Pintado, M.E. (2018), Novel Eco-Friendly Method to Extract Keratin from Hair. ACS Sustainable Chemistry and Engineering, 2018, 6(9), 12268-12274http://hdl.handle.net/10400.14/26506Pig slaughtering for meat production is a major worldwide industry that generates many byproducts that can cause environmental problems. Nonetheless, it is possible to have a management of these residues toward the reuse and valorization of these byproducts. One opportunity focuses on the extraction of value-added compounds such as keratin since pig hair is composed by 80% of this protein. There are some methods for keratin extraction from human hair as other sources such as wool and feathers, but they bring many problems such as pollution, time-consumption, and high costs. This work uses a commercial detergent belonging to the category of degreasers, capable of fast and efficient dissolution of pig hair, followed by a simple filtration to remove residues from skin trimmings with fat and lard. The resulting solution is submitted to an ultrafiltration process to obtain a solution with higher protein content and purity, both at laboratory scale and pilot scale-up. Use of this keratin green extraction method allows to obtain a keratin product with protein purity up to 70% with a yield extraction of about 50%, which although lower than the previous methods allow protein integrity and cleaner technology. This method allows a relevant valorization of pig hair, using for the first time a simple, cost-effective, and environmentally friendly approach.engKeratinUltrafiltrationExtractionValorizationResiduesjournal article10.1021/acssuschemeng.8b0268085052285533000443924100128