Sousa, TeresaVale, InêsRosadas, MartaSilva, Inês V.Ribeiro, Viviana P.Oliveira, Ana L.2025-03-262025-03-262025-06http://hdl.handle.net/10400.14/52816Burns affect 11 million people globally each year with 180,000 associated fatalities. This study proposes a multilayer hybrid dressing combining a silk fibroin (SF) textile with decellularized porcine small intestine (dPSI) capable of simultaneously provide wound protection and tissue regeneration. A silk sericin (SS) hydrogel was embedded into the decellularized tissue ensuring the integration with the textile layer while promoting anti-inflammatory benefits, enhancing the hybrid dressing’s biological performance.engreport