Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.14/9968
Título: Effect of in vitro digestion upon the antioxidant capacity of aqueous extracts of Agrimonia eupatoria, Rubus idaeus, Salvia sp. and Satureja montana
Autor: Gião, Maria S.
Gomes, Susana
Madureira, Ana R.
Faria, Ana
Pestana, Diogo
Calhau, Conceição
Pintado, M. E.
Azevedo, Isabel
Malcata, F. Xavier
Palavras-chave: Agrimony
Raspberry
Sage
Savory
Caco-2 cells
Antioxidant profile
Data: 2012
Editora: Elsevier
Citação: GIÃO, Maria S... [et al.] - Effect of in vitro digestion upon the antioxidant capacity of aqueous extracts of Agrimonia eupatoria, Rubus idaeus, Salvia sp. and Satureja montana. Food Chemistry. ISSN 0308-8146. Vol. 131, n.º 3 (2012), p. 761-767
Resumo: An in vitro digestion/Caco-2 cell culture model was used to assess the stability and bioavailability of phenolic compounds in aqueous extracts of four herbal infusions, traditionally used as functional drinks in Portugal. Alterations in antioxidant power were monitored by ABTS +, whereas the profile of phenolic compounds was ascertained by HPLC-DAD. The bioavailability of rutin – an important flavonoid present in such extracts, and thus a representative of those compounds, was assessed across Caco-2 cells via LC– MS/MS. Our results indicate that several antioxidant compounds are not affected by the (simulated) digestive process, whereas others undergo decreases in their activity throughout said process; a few have their antioxidant capacity hampered under stomach-like conditions. It was also found that rutin can be transported across the Caco-2 cell barrier.
Peer review: yes
URI: http://hdl.handle.net/10400.14/9968
Versão do Editor: doi:10.1016/j.foodchem.2011.09.030
Aparece nas colecções:CBQF - Artigos em revistas internacionais com Arbitragem / Papers in international journals with Peer-review

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