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|Título:||How performance of integrated systems of reaction and separation relates to that of parallel and sequential configurations|
|Autor:||Paiva, A. L.|
Malcata, F. X.
|Citação:||PAIVA, A. L.; MALCATA, F. X. - reaction and separation relates to that of parallel and sequential configurations. Bioprocess Engineering. ISSN 0178-515X. Vol.22 (2000), p. 149-158|
|Resumo:||Given the thermodynamic and kinetic limitations which often constrain the extent of chemical reactions and post-reactional separation processes, and therefore constrain the yield and the degree of purity of the resulting products, integration of reaction and separation in a single unit has been under the scope of several bioengineering researchers in recent years. It is the aim of this work to compare the performance of a cascade of N reactor/separator sets, either in series or in parallel, with that of an integrated reaction/separation unit. In order to do so, a Michaelis-Menten reaction in dilute substrate solutions (i.e. a pseudo ®rst order reaction) was considered to take place in either con®guration and, under the same reaction and separation conditions, comparison of the performance and ef®ciency of these con®gurations was made in terms of fractional recovery of pure product, total time required to achieve such recovery and rate of recovery. It was concluded that: (i) the series combination of reactor/separator sets yields better results, both in terms of fractional amount of product recovered and time required to do so, than the parallel combination; and (ii) the integrated approach is much more time- and cost-effective than plain cascading, thus making it very attractive from an economic point of view.|
|Versão do Editor:||http://www.springerlink.com/content/hmyqaxvduega47we/|
|Aparece nas colecções:||ESB - Artigos em revistas internacionais com Arbitragem / Papers in international journals with Peer-review|
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