Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.14/12863
Título: A Review on Antifungal Activity of Mushroom (Basidiomycetes) Extracts and Isolated Compounds
Autor: Alves, Maria José
Ferreira, Isabel C. F. R.
Dias, Joana
Teixeira, Vânia
Martins, Anabela
Pintado, M. E.
Palavras-chave: Antifungal activity
Antifungal proteins
Basidiomycetes
Grifolin
Data: 2013
Editora: Bentham Science Publishers
Citação: ALVES, Maria José...[et al.] - A Review on Antifungal Activity of Mushroom (Basidiomycetes) Extracts and Isolated Compounds. Current Topics in Medicinal Chemistry.ISSN 1568-0266. Vol. 13, n.º 21 (2013), 2648-2659
Resumo: The present review reports the antifungal activity of mushroom extracts and isolated compounds including high (e.g. peptides and proteins) and low (e.g. sesquiterpenes and other terpenes, steroids, organic acids, acylcyclopentenediones and quinolines) molecular weight compounds. Most of the studies available on literature focused on screening of antifungal activity of mushroom extracts, rather than of isolated compounds. Data indicate that mushroom extracts are mainly tested against different Candida species, while mushroom compounds are mostly tested upon other fungi. Therefore, the potential of these compounds might be more useful in food industry than in clinics. Oudemansiella canarii and Agaricus bisporus methanolic extracts proved to be the most active mushroom extracts against Candida spp. Grifolin, isolated from Albatrellus dispansus, seemed to be the most active compound against phytopathogenic fungi. Further studies should be performed in order to better understand the mechanism of action of this and other antifungal compounds as well as safety issues.
Peer review: yes
URI: http://hdl.handle.net/10400.14/12863
Aparece nas colecções:CBQF - Artigos em revistas internacionais com Arbitragem / Papers in international journals with Peer-review

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