Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.14/10025
Título: The Portuguese Paradox: why do some inhabitants of Portugal appear to live so long when their diet is based on whey cheese?
Autor: Tavares, Tânia G.
Malcata, F. Xavier
Palavras-chave: Bioactive peptides
Plant protease
Enzymatic hydrolysis
Whey proteins
Data: 2012
Editora: Elsevier
Citação: TAVARES, Tânia G.; MALCATA, F. Xavier - The Portuguese Paradox: why do some inhabitants of Portugal appear to live so long when their diet is based on whey cheese?.Food Chemistry. ISSN 0308-8146. Vol. 131, n.º 3 (2012), p. 727-729
Resumo: The remarkable longevity of people in specific regions of Portugal, whose diets are based on whey cheese, has puzzled researchers for quite some time. Our data indicate that several oligopeptides are released from glycomacropeptide (originated in j-casein) and a-lactalbumin – and one surprisingly from b-lactoglobulin, by plant proteases previously used in cheesemaking. A few of such peptides (e.g. DKVGINYW, KGYGGVSLPEW and DAQSAPLRVY) exhibit unusually strong antihypertensive roles in vitro, following generation in situ or synthesis de novo. The activities of the latter two are not significantly affected by simulated gastrointestinal digestion, despite undergoing partial hydrolysis. This piece of information is rather promising toward more comprehensive attempts to scientifically rationalise this Portuguese Paradox.
Descrição: Rapid Communication
Peer review: yes
URI: http://hdl.handle.net/10400.14/10025
Versão do Editor: doi: 10.1016/j.foodchem.2011.09.052
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